Clinical Practice Guidelines

This educational session covers:

*Review of evidence-based medicine and hierarchies of evidence

*Rapid review process for clinical effectiveness assessment

*Formulating searchable and answerable clinical questions using PICOTS framework

*GRADE process for rating quality of evidence in systematic reviews and grading the strength of recommendation (creating GRADE evidence profile (EP) and summary of findings (SoF) 

Training materials will be provided upon request. 

The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system   is widely used and considered the standard in guideline development. In GRADE, grades have two components: a two-level representation of the strength of recommendation (strong or weak) and a four-level representation of the quality of the evidence (high, moderate, low, and very low).

Video: Overview of the GRADE approach in guideline development